A PHEIC is defined by WHO as "an extraordinary event which is determined to constitute a public health risk to other States through the international spread of disease and to potentially require a coordinated international response" under International Health Regulations, with recent examples including COVID-19, Monkeypox, and wild polio (International Health Regulations 2005, linked here under publications - WHO - International Health Regulations, International Health Regulations - Annex II, Pan American Health Organization, NPR).

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